Heart Failure

Heart failure occurs when the heart struggles to pump blood effectively, often due to prior damage or chronic conditions. Stem cells can play a vital role in restoring heart function by promoting the growth of new blood vessels and repairing damaged cardiac tissue. With CellMark360’s automated, closed-loop system, your stem cells are isolated in a sterile, reproducible process, ensuring they are ready to support your heart’s recovery and improve its ability to pump efficiently.

How Your Own Stem Cells Support Healing for Heart Failure

Improves Heart Function

Adipose-derived cells help restore cardiac output by increasing ejection fraction, supporting healthier heart muscle contraction and improved circulation.

Enhances Physical Endurance

Studies show increased 6-minute walk distance and exercise duration, helping patients regain the ability to perform daily activities without fatigue or breathlessness.

Reduces Symptoms Like Angina

SVF and ASCs alleviate chest pain and improve clinical classification scores (e.g., CCS and NYHA), enhancing quality of life and reducing hospital visits.

Safe and Autologous

Using your own adipose-derived stem cells minimizes risk of immune rejection. Across all major studies, no serious adverse events were reported.

Research confirms ADSCs reduce inflammation, repair cartilage, and improve function.

SVF for Ischemic Cardiomyopathy – 28 Patients (Chronic Heart Failure)

Study Summary:

Intramyocardial implantation of SVF in patients with low ejection fraction and exercise intolerance.

Results at 6 months:

*EF increased from 29% to 35%

*6-minute walk distance improved by >80 meters

*No serious adverse events

(Source: JAMA Surg. 2016)

MyStromalCell Trial – 60 Patients (Chronic Ischemic Heart Disease)

Study Summary:

ASCs injected into the heart in patients with refractory angina and reduced exercise tolerance.

Results at 6 months:

*Exercise duration ↑ by 22 sec (p=0.034)

*METs ↑ by 0.2 (p=0.048)

*Angina class improved from 2.5 to 1.8 (p=0.002)

*Placebo group worsened over time

(Source: Stem Cells Int. 2017)

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