Peripheral Artery Disease

Peripheral artery disease (PAD) restricts blood flow to the limbs, often causing pain, reduced mobility, and a higher risk of complications. Personal stem cell therapy can help by stimulating angiogenesis—the growth of new blood vessels—to improve circulation. CellMark360’s gentle isolation process ensures your adipose-derived stem cells are highly viable and capable of supporting vascular repair, potentially alleviating symptoms and enhancing quality of life for PAD patients.

How Your Own Stem Cells Support Healing for Peripheral Artery Disease

Restores Blood Flow

Autologous stem cells (from your own fat tissue) help form new blood vessels (angiogenesis), restoring circulation to oxygen-starved tissues.

Heals Chronic Ulcers

Studies show significant wound healing in patients with critical limb ischemia (CLI), reducing the need for amputations.

Relieves Pain and Improves Mobility

Patients experience less pain and can walk farther—restoring daily function and reducing disability.

Safe and Natural

Using your own cells avoids immune rejection. Clinical trials report no major side effects, offering a safer alternative for those ineligible for surgery.

Research confirms ADSCs reduce inflammation, repair cartilage, and improve function.

Darinskas et al. (2017) – 15 CLI Patients, No Surgical Options

Study Summary:

Patients with severe PAD received SVF injections directly into affected limbs.

Results:

*86.7% showed clinical improvement

*Only 13.3% required amputation (and healed fully)

*All ulcers completely healed

*Pain decreased, walking improved, and new blood vessels were confirmed by imaging

(Source: Darinskas Study – D-NB)

Meta-Analysis – Multiple PAD Studies, Broad Population

Study Summary:

Review of autologous stem cell therapy across PAD clinical trials.

Results:

*37% reduced risk of amputation

*59% improved wound healing

*18% increase in amputation-free survival

*No increase in overall mortality

(Source: AHA Journals Meta-Analysis)

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